Treating Warfarin-Related Intracerebral Hemorrhage

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Predictors of outcome in warfarin-related intracerebral hemorrhage.

BACKGROUND Intracerebral hemorrhage (ICH) associated with warfarin sodium therapy is becoming more common as the use of this medication increases in the aging population. OBJECTIVE To delineate factors associated with early mortality, determine variables responsible for poor functional outcome, and evaluate possible reasons for expansion of hemorrhage and associated parenchymal edema. DESIG...

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Warfarin-associated intracerebral hemorrhage after ischemic stroke.

BACKGROUND AND PURPOSE The aim was to investigate the risk of intracerebral hemorrhage (ICH) in patients with ischemic stroke taking warfarin and whether this risk changed over time. METHODS Between 2001 and 2008, the Swedish Stroke Register registered 12,790 patients with ischemic stroke discharged on warfarin. The patients was studied in two 4-year periods (inclusion 2001-2004: follow-up un...

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Experimental model of warfarin-associated intracerebral hemorrhage.

BACKGROUND AND PURPOSE Future demographic changes predict an increase in the number of patients with atrial fibrillation. As long-term anticoagulation for the prevention of ischemic strokes becomes more prevalent, the burden of warfarin-associated intracerebral hemorrhage (W-ICH) is likely to grow. However, little is known about the clinical aspects and pathophysiologic mechanisms of W-ICH. Thi...

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Warfarin-Induced Intracerebral Hemorrhage Associated with Microbleeds

BACKGROUND Microbleeds (MBs), proposed as a biomarker for microangiopathy, have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear. CASE REPORT We describe two patients who developed warfarin-induced ICH at the site of MBs documented in previou...

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Intracerebral hemorrhage and warfarin: perceived versus actual risk.

See related article, pages 2431–2435. Oral anticoagulation (OAC) reduces risk of thromboembolism and is recommended for a wide range of indications, including deep vein thrombosis, pulmonary embolism, and mechanical heart valves, although the most common reason for OAC use is still atrial fibrillation (AF).1 For over 60 years, the vitamin K antagonist class of drugs (eg, warfarin) has been the ...

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ژورنال

عنوان ژورنال: Stroke

سال: 2006

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.0000195152.46506.3e